The PCB works fine for me, so this is a bit of nit-picking.
But I couldn't help noticing that the switching loop for U4 is unnecessarily long, because the output diode D1 is placed so far from the rest of the parts. This will increase ripple and noise emissions from the switcher.
I think it would be possible to move R2 elsewhere so that there is space for D1 near C4:
